The theoretical background of the research problem is presented, the importance of the factor of professional activity in the moral self-determination is proved and the choice of professional groups included in the study is justified. The results of an empirical study carried out on a sample of students of the faculties of psychology, economics, advertising (n = 114, 18–35 years old) using the author’s methodology «Personal moral self-determination» (A. E. Vorobieva and A. B. Kupreichenko).